The spear bomb is most effective for this (The first Oroborous Scroll reward) They are very weak to explosives, which can straight up one-shot them.They cannot be stunlocked, so attempting to damage race them will just end with you flying across the room.Ghouls are most vulnerable when they are charging up an Acid spit, get in a few hits and then jump over it before it finishes.Remember this and be cautious so you don’t get caught off guard Every pile of rubble could be a ghoul.Avoid their bombs at all costs, not only do they deal significant damage, they also apply high knockback, leaving you in a seriously disadvantageous position.Time is of the essence, if you take too long they will teleport away, forcing you to go after them again.Like most ranged enemies, if you get up in their face you can stunlock them.
Use the crossbow to damage them from afar, and then run up and lay on a beatdown before they recover.
you can see the Guard tense up when they are about to shoot, Use this to your advantage.Take care time your approach so that they can’t hit you with their melee attack, since it will almost definitely send you flying across the room, allowing the Guard to hit you with its ranged attack.Much deadlier version of the Ranged Bandits, with better aiming, a Melee attack, spread shot, and more damage.You will have to jump sooner then you think. Their run attack is much faster than one would expect.The ranged attack can simply be jumped over, but is most deadly when used offscreen.Pretty much a faster, stronger, tankier version of the Melee Bandits with a weak ranged attack.You can duck/Roll to dodge their shuriken’s.Another option is to throw bombs at them, while dealing with the melee enemies (When they are in groups).Focus them first over other enemies, they can’t do much when you close the gap.Alternatively, attack them from afar with the crossbow, and do a running leap over them when they try to run at you.Get in 2-3 attacks, and then back off when they start to wind up a slam, before going back in after to prevent them from starting a run attack.